Circadian Rhythms

 

 

Humans are by nature diurnal (day orientated) as opposed to nocturnal (night orientated) beings, meaning that our physiological functions are geared towards day time activity and night time rest.

Research has shown in fact that our physiological functions fluctuate in cycles, or rhythms, which are regulated by an internal biological clock in the brain. These rhythms range from minutes, for example in the stages of sleep, to days, for example in the female menstruation cycle.

Studies have shown that the main physiological functions such as core body temperature, hormone production, heart rate, blood pressure, gastric activity, and the sleep/wake cycle, all have cycles or rhythms of approximately 25 hours. These cycles are known as circadian rhythms (from the Latin 'circa' = about, and 'dia' = a day).

Normally our circadian rhythms are synchronized to one another by the internal biological clock, and entrained (daily reset) to the 24 hour day/night cycle by external time cues, namely the variation in sunlight and the increase in environmental and family activity around us.

A typical cycle of core body temperature, for example, normally has two peaks (around 1130hrs and 1900hrs) and two troughs (around 0400hrs and 1400hrs) - see attached Core Body Temperature Graph.

When we work rotating shifts, we have to adjust our natural sleep/wake cycle to suit whichever shift we are on. However, our other circadian rhythms do not adjust instantaneously - in fact different rhythms change at different rates - and typically take a week or more to adjust to the new sleep/ wake cycle. A useful analogy is that of an orchestra where initially the different sections are playing in harmony under the one conductor. If another conductor appears and starts a different beat there will be discord as the different sections change at their own rate to the new beat.

Rotating onto night shift causes the greatest disruption to our circadian rhythms as we attempt to remain active and alert during the night when our circadian rhythms are falling to their lowest and try to sleep during the day when our circadian rhythms are rising to their peaks. When this happens we can experience sleep loss and gastrointestinal problems. Loss of sleep leads to, fatigue, irritability and lethargy and a decline in performance such as poorer concentration, alertness and decision making. This in turn increases the risk of making errors which may effect not only our own safety but also that of our colleagues.

How quickly our circadian rhythms adjust to a new sleep/wake cycle depends on internal factors such as the age, gender, physical health and chronotype ( see 'Larks and Owls' ) of the individual, and external factors such as the shift pattern and work load, and family and social circumstances.

If we rotate onto another shift before our circadian rhythms have had time to adjust to one sleep/wake cycle, then our circadian rhythms may become in a perpetual state of internal desynchronisation, where they are never fully synchronised to one another.

Although the effects of shift work on our circadian rhythms cannot be eliminated completely, there are steps that can be taken at both the organisational level and individual level to minimize these effects.

 

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