*  Sandra & Teresa Alvaro

..... when Sandra gave a donation of ovarian tissue in order for her sister Teresa to conceive it was the FIRST time in the world that the operation had been carried out involving non-identical sisters - February 2006. The operation was carried out by Professor Jacques Donnez, head of the Department of Gynaecology at the Catholic University of Louvain in Brussels

* Sandra Campopiano

..... FIRST ever human resources director at Arrow Electronics (UK) in 1995

* Sandra Chalmers

..... one of the FIRST women announcers in the BBC Northern Region and the FIRST woman BBC local radio station manager (Stoke)

* Sandra Cottom

..... FIRST woman ambulance station boss in Greater Manchester, England, in 1993 when she beat five other candidates to the post of relief manager to run stations while regular managers are away

* Sandra Cottrell

 born 1945

..... started the FIRST Elvis Presley fan club ever in her hometown of Tupelo, Missouri and which she named The Elvis Presley Home Town Fan Club

* Sandra Dawson

..... FIRST woman Master of an all-male college in 1998 when appointed to Sidney Sussex, formerly an all-male Cambridge college. The college was 400 years old and was one of the first to admit women in 1976

* Sandra Leyland

..... one of the FIRST women to be adopted for election for the European Parliament when she contested South West Yorkshire for the Green Party

* Sandra McDonald

..... FIRST woman and FIRST English person to be named the Public Guardian for Scotland (April 2005) and makes her responsible for looking after the financial interests of vulnerable and incapacitated adults. Sandra is originally from Marple near Manchester but now lives in Edinburgh

* Sandra Mcleod

..... in 1995 became only the third woman in Britain to achieve top status as an athletics starter when she became qualified to fire her starting pistol at international meetings. She became her home town's (Wigan, Lancashire) FIRST international athlete and scooped dozens of titles and medals

* Sandra Murphy

..... in 1990 she became the FIRST conservation officer for cemeteries in Britain when appointed in Cardiff, Wales, where she will look after wildlife and catalogue the thousands of memorials and headstones in the city's seven cemeteries

* Sandra Day O'Connor

born 1930

..... FIRST woman judge in the Supreme Court in America. In 1972 she ran for the State Senate and was elected Majority Leader - the FIRST woman to hold this post.  After graduating she tried to obtain work in a private law firm in Los Angeles but prejudice against women led her to become a Deputy County Attorney in San Mateo, California. After spending five years as a full time housewife bringing up her five sons she returned to work in 1965 as an Assistant Attorney General in Arizona, ran successfully for the State Senate in 1970 and 1972, was elected and in 1974 won a place on the Maricopa County Superior Court Bench. In 1979 she was appointed to the Arizona Court of Appeals

* Sandra Preston

..... FIRST woman to join Manchester Airport's technician team where she repaired everything from air-bridges, lifts, escalators and baggage systems. Sandra has been in the job for 12 years and in 2003 was joined by Amanda Deane who has taken up an engineering apprenticeship thereby becoming Sandra's FIRST female colleague

* Sandra Shaw